San Diego, CA, USA, and Munich, Germany – October 21, 2025 – selectION, Inc. (“selectION” or the “Company”), a clinical-stage biopharmaceutical company developing novel treatments for T cell-mediated autoimmune diseases, today announced the successful completion of its phase 1b proof-of-concept trial evaluating si-544, a first-in-class Kv1.3 blocker in patients diagnosed with psoriasis vulgaris.

His groundbreaking work on T cells and immune regulation has paved the way for innovative immunotherapies, offering new hope to millions of patients living with autoimmune and inflammatory diseases. Dr. Ramsdell’s…

New study follows completion of first-in-human Phase 1b trial in atopic dermatitis patients, in which selectION observed safety and tolerability of si-544 in the treatment of T cell autoimmunity Recruitment…

si-544 was well tolerated with no serious adverse effects, dose limiting toxicities, or safety signals observed 75% of patients receiving si-544 experienced objective clinical improvement, of which 44% achieved clear…

By Cormac Sheridan, Staff Writer – Published by BioWorld™ – The coming months represent a crucial phase in the development of Selection Inc., a U.S.-German firm that is tackling a…

Ongoing phase 1b trial is designed to evaluate safety, tolerability, and efficacy of si-544 in T-cell mediated autoimmunity Dosing of MAD stage has been initiated; first results expected for late…

Phase 1b trial is designed to evaluate safety, tolerability, and efficacy of potent Kv1.3 blocker in T-cell mediated autoimmunity – San Diego, CA, USA, and Munich, Germany – September 12,…

Novel ion channel blocker designed to combine high efficacy and durable response while maintaining full immune system functionality – San Diego, CA, USA, and Munich, Germany – May 09, 2022…

si-544, a Kv1.3 blocker with class leading selectivity and excellent preclinical safety profile, scheduled to advance towards clinical development in early 2021 SAN DIEGO, September 16, 2020 – selectION, Inc.…

SAN DIEGO, May 31, 2019 – selectION, Inc., a biotherapeutic company focused on the development of peptide ion channel blockers with class leading selectivity, announced today it has received a…

SAN DIEGO, November 30, 2018 – selectION, Inc. a biotechnology company that has established an efficient technology platform to develop novel peptide therapies incorporating highly selective peptide blockers for ion…

SAN DIEGO, August 29, 2018 – selectION, Inc. a biotechnology company that has established an efficient technology platform to develop novel peptide therapies incorporating highly selective peptide blockers for ion…